Health technology assessment: time for a randomised controlled trial of the role of lung volume reduction surgery in the treatment of emphysema. The Lung Volume Reduction Surgery Trial Project Team.
نویسندگان
چکیده
منابع مشابه
The role of the emphysema multidisciplinary team in a successful lung volume reduction surgery programme†.
OBJECTIVES Lung volume reduction surgery (LVRS) for advanced emphysema is well established, with strong evidence from the National Emphysema Treatment Trial. However, there is still reluctance to offer the procedure, and many have looked for alternative, unproven treatments. The multidisciplinary approach has been well established in treatment of lung cancer and, more recently, in coronary arte...
متن کاملEndobronchial valves in a highly parsed emphysema population
Lung volume reduction surgery is a thoracic surgical procedure whereby the hyperexpanded lungs of patients with severe emphysema are reduced in size by surgical excision of, ideally, the areas that are most severely destroyed. This operation, usually done bilaterally and almost always by video-assisted thoracoscopy, substantially improves pulmonary function, dyspnoea, and quality of life in app...
متن کاملBronchoscopic lung volume reduction with endobronchial valves for patients with heterogeneous emphysema and intact interlobar fissures (the BeLieVeR-HIFi study): a randomised controlled trial
BACKGROUND Lung volume reduction surgery improves survival in selected patients with emphysema, and has generated interest in bronchoscopic approaches that might achieve the same effect with less morbidity and mortality. Previous trials with endobronchial valves have yielded modest group benefits because when collateral ventilation is present it prevents lobar atelectasis. METHODS We did a si...
متن کاملCost effectiveness of lung-volume-reduction surgery for patients with severe emphysema.
BACKGROUND The National Emphysema Treatment Trial, a randomized clinical trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema, included a prospective economic analysis. METHODS After pulmonary rehabilitation, 1218 patients at 17 medical centers were randomly assigned to lung-volume-reduction surgery or continued medical treatment. Costs for the use of medica...
متن کاملHeterogeneity of lung volume reduction surgery outcomes in patients selected by use of evidence-based criteria.
BACKGROUND Despite its benefit, lung volume reduction surgery (LVRS) is underused, partially because of the heterogeneous responses and lack of recent outcomes data. METHODS Data from 59 consecutive emphysema patients who underwent LVRS were analyzed. The proportion of patients responding based on 6-minute walk distance (6-MWD), exercise capacity (watts), and forced expiratory volume in 1 sec...
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عنوان ژورنال:
- Thorax
دوره 52 9 شماره
صفحات -
تاریخ انتشار 1997